The breakdown of glucose is most efficient in the presence of oxygen (aerobic respiration) and produces the most ATP, which is essential for powering cellular functions. The mitochondria is the key ...

aDepartment of Clinical Biochemistry and Pharmacology, Ben-Gurion University of the Negev, P.O. Box 653, Beer Sheva 84105, Israel bDepartment of Pathology and Laboratory Medicine, Rutgers-New Jersey ...

Oxidative phosphorylation sharply decreases upon classical macrophage activation, as mitochondria are thought to shift from ATP production towards accumulating signals that amplify effector function.

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Chloride ions are important inducers of salt ...

An increase in oxidative stress resulting from increased cardiac generation of reactive oxygen ... coronary vascular endothelial dysfunction and peroxynitrite-induced inhibition of myocardial ...

This unleashes transcription of mtDNA genes involved in oxidative phosphorylation, producing the much-needed ATP. Neuronal excitation triggers an influx of calcium into mitochondria, triggering ...

Institute of Medical Biochemistry and Laboratory Diagnostics, and 4th Department of Internal Medicine, General University Hospital in Prague and 1st Faculty of Medicine, Charles University, Na Bojišti ...

Genetic approaches to deplete ADGRA3 expression in vitro resulted in reduced expression of thermogenic genes including Ucp1, reduced basal respiration and metabolic activity as reflected by reduced ...

2020). Thus, it can be inferred that the UPRmt generally slows mitochondrial activity for organelle recovery but may raise the risk of declining oxidative phosphorylation, membrane potential loss, and ...

Defects in the oxidative phosphorylation (OXPHOS) system — the final biochemical pathway in the production of ATP — result in devastating, mainly multisystem diseases. The OXPHOS system is ...