Groundbreaking research on the differentiation of embryonic stem cells (ESCs ... aberrant transcript were detected in retinal organoids, co-incident with photoreceptor differentiation and the ...

They house the retina’s light-responsive outer photoreceptor segment. RPE cells displaying cobblestone morphology. Cells were immunolabeled with tight-junction ZO-1 marker (shown in green ...

Using the stem cells, the researchers made "retinal sheets" that are enriched in immature versions of the cone photoreceptor cells, which could become mature cone cells when cultured in the lab.

Based on in situ hybridization and hypothyroid studies, thyroid hormone appears to target photoreceptor development. The hormone may be acting in at least two ways. It could instruct neuronal ...

It also disrupts blood vessels that are situated behind the retina. This disrupts normal cell metabolism, leading to the death of photoreceptor cells and, eventually, geographic atrophy ...

reveals for the first time that photoreceptor cells in the mammalian retina exhibit planar polarity, meaning that their light-sensitive cilia orient themselves in a coordinated manner in the plane ...

The light-detecting part of the retina is formed of rod and cone photoreceptor cells that are responsible for everything we see. The lower third of this image depicts the layer of blood vessels ...