Systemic lupus erythematosus (SLE) can involve many parts of the eye ... thrombocytopenia), immunological disorder (anti-DNA antibody, anti-Sm antibody and false positive Venereal Disease Research ...

病例信息患者吕*，男，33岁，主因“发现血肌酐升高3月，周身水肿半月”入院。现病史：患者入院前3月因“原发性血小板减少症”复诊时发现血肌酐升高，为106μmol/L，当时无尿量及尿色改变，无下肢水肿，无恶心、呕吐，无胸闷憋、气，无脱发、光过敏，无皮疹、关节肿痛等，患者未行诊治。入院前半月患者无明显诱因出现周身水 ...

Genentech has shared positive data from the Phase III REGENCY trial with regulators in the US and EU. Roche’s subsidiary ...

Roche (SIX: RO, ROG; OTCQX: RHHBY) announced today that a detailed analysis of its phase III REGENCY trial of Gazyva®/Gazyvaro® (obinutuzumab) in people with active lupus nephritis (LN) was published ...

We also detected antibodies specific for phosphorylation-dependent post-translational modifications, which may have an important role in breaking immune tolerance in SLE (data not shown ...

Connective tissue diseases (CTDs) increase the risk for adverse maternal and fetal outcomes during pregnancy, with varying impacts across different CTD subtypes, according to study results published ...

Breakthrough research and investor enthusiasm prompted Cullinan Therapeutics to redirect one of its cancer programs toward ...

Objectives To examine the safety and efficacy of rontalizumab, a humanised IgG1 anti-interferon α (anti-IFN-α) monoclonal antibody, in patients with moderate-to-severe systemic lupus erythematosus ...

Objective Hypertension (HTN) is common in systemic lupus erythematosus (SLE), representing a key risk factor for cardiovascular and renal disease. We described HTN treatment patterns in SLE, evaluated ...

Objectives Systemic lupus erythematosus (SLE) is a chronic autoimmune disease of considerable genetic predisposition. Genome-wide association studies have identified tens of common variants for SLE.