Serum liver tests revealed an elevated aP of 2.5 × ULN, γ-GT of 5.5 × ULN, mildly elevated transaminases (AST of 1.7 × ULN; ALT of 2.1 × ULN), and normal bilirubin. Serum AMA (1:3840 ...

High serum transaminases usually result from hepatocyte necrosis associated with acute viral infections, toxic or ischemic injury. By contrast, there is normal-to-moderate elevation of ...

Obtain urinalyses, serum electrolytes to evaluate renal tubular function. Measure serum transaminases, bilirubin before initiating therapy then every 2 weeks during 1 st month, then monthly.