Nitrogen signal transduction is a crucial process in various ... the complexity and significance of nitrogen signaling and PII protein regulation. Recent studies have revealed that PII proteins ...

Increased understanding of signal transduction mechanisms and gene regulation involved in immune responses has created opportunities for the discovery of novel therapeutic compounds useful in treating ...

Attisano, J.L. Wrana, "MADR1, a MAD-related protein that functions in BMP2 signaling pathways," Cell ... If there is one thing that is known about the mechanisms that govern signal transduction, it's ...

S. Gupta, T. Barrett, A.J. Whitmarsh, J. Cavanagh, H.K. Sluss, B. Dérijard, R.J. Davis, "Selective interaction of JNK protein isoforms with transcription factors ...

Recent studies showed that a peptide, the protein transduction domain (PTD) from HIV Tat, could improve the distribution of cytoplasmic reporter proteins when administered systemically as fusion ...

The PhoP response regulator and the cognate sensor kinase PhoQ form one of the two-component signal transduction systems that is highly conserved in bacteria. The PhoP/PhoQ system is a crucial ...

A new study shows how an anticancer drug triggers an “outside in” signal that gets it sucked into a cancer cell. The work, published Jan. 29 in Nature Communications, reveals ...

Innovative designs of GPCRs with enhanced signaling and stability offer new insights for drug discovery and synthetic biology ...

The SV is unique to fish and coronet cells are CSF-contacting neurons. Here, we discuss the universality and diversity of signal transduction pathways that regulate vertebrate seasonal reproduction.

尽管如此，本研究为 65 岁以上老年人接种三种基于蛋白的含 XBB 疫苗后的中和抗体反应提供了重要证据，为优化老年人群疫苗接种策略、增强对新兴 SARS-CoV-2 变体的中和免疫力提供了关键信息。未来需进一步研究不同给药途径疫苗诱导的免疫特征、年龄对加强免疫后免疫力持久性的影响以及疫苗对新变体的效力等问题，以更好地应对新冠疫情，保障老年人群健康。

Septerna has a market cap of $750mn and $130mn in cash and ST investments. Discover SEPN's groundbreaking drug discovery ...

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