G protein-coupled receptors (GPCRs) are integral membrane proteins with seven membrane-spanning helices. Upon binding to a ligand – which can range from small molecules like cyclic AMP to ...

which are activated by G protein–coupled receptors (GPCRs) and consist of alpha, beta, and gamma subunits, and the monomeric small G proteins, which belong to the Ras superfamily of small GTPases.

Researchers from Columbia University Irving Medical Center published data from a study that assessed GiGA1, a selective G protein-gated inwardly rectifying potassium channel (GIRK) activator, in ...