A recent study investigates the role of the deubiquitinase OTUB1 in vascular smooth muscle cells (VSMCs) within the context of atherosclerosis, a disease characterized by lipid accumulation and ...

A computational model uses computer simulation and modeling techniques ... including vascular elasticity, endothelial function, and smooth muscle cells, addressing limitations in structure and ...

Despite global efforts to prevent and treat cardiovascular diseases, myocardial infarction and stroke remain leading causes of mortality worldwide (1, 2). The common pathological link between these ...

The ECM (extracellular matrix) provides the microenvironmental niche sensed by resident vascular smooth muscle cells (VSMCs). Aging and disease are associated with dramatic changes in ECM composition ...

known as cell differentiation, holds the key to understanding developmental biology and advancing regenerative medicine. A team of researchers in Japan has developed a new computational tool ...

Columbia researchers created an AI model that predicts gene activity in any human cell, advancing disease research and treatment. It has already uncovered mechanisms behind pediatric leukemia and may ...

Department of Cardiology, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, China (X. Han, Y.L., L.S., B.H., B.Z.). CAS CEMCS-CUHK Joint Laboratories, New Cornerstone Science ...

peft-sam implements several PEFT (Parameter Efficient Fine-Tuning) methods for Segment Anything Model (SAM) in the biomedical imaging domain.