How are induced pluripotent stem (iPS) cells different from embryonic stem (ES) cells? What can we use iPS cells for? ES cells were originally derived from the inner cell mass (ICM) or epiblast of ...

In a groundbreaking shift in our understanding of mutations, researchers have discovered types of DNA damage in healthy cells that can remain unrepaired for years. While most types of DNA damage are ...

Research Interests: Somatic Stem Cells and Aging, Genetic Mechanisms of Stem Cell Maintenance, Therapeutic Approaches to Tissue Rejuvenation, Mouse Models of Hair Graying, Melanocyte Stem Cells and ...

Stem cells derived from adult somatic cells “will carry the mutational history of their past, as well as of any new mutations that occur when you are reprogramming them or growing them in culture,” ...

New research shows persistent DNA lesions in stem cells contribute to mutations, with links to blood cancers and external mutagens.

Stem-cell research has enormous potential value ... the first mammal cloned from the cell of an adult animal.) A somatic cell could be taken from the recipient individual, its nucleus inserted ...

We were so excited,” Liu reminisced. The team then confirmed that the iPSCs that they had identified based on physical characteristics exhibited the associated genetic traits of the stem cells they ...

Therefore the stem-like cells are likely to exhibit a distinct gene expression program that is compatible ... single-cell transcriptomics data to reduce cellular heterogeneity in tumors. These ...

We provide locally derived human pluripotent stem cell lines and generate induced pluripotent stem cell (iPSC) lines from somatic cells provided by the client. BSCC operates on a fee-for-service basis ...

Hematopoietic stem cell gene therapy (HSC-GT ... induced hematopoietic stress were found to modulate HSC activity and somatic ...