Somatostatin-expressing neurons of the entopeduncular nucleus (EPNSst+) provide a limbic output of the basal ganglia and co-release GABA and Glutamate in their projection to the lateral habenula, a ...

Figure 1. Location of the deep brain structures. Putamen, Pu; Caudate, Ca; external globus pallidus, GPe; internal globus pallidus, GPi; Red nucleus, RN; substantia nigra pars compacta, SNc; nigra ...

Starting from whole-brain probabilistic tractography, all streamlines through the SNc reaching the thalamus were counted, separately for each hemisphere, after excluding streamlines through the ...

The subthalamic nucleus (STN) has an important role in locomotion, as evidenced by the successful use of high-frequency stimulation of this structure as treatment for Parkinson disease. There is ...

Somatostatin-expressing neurons of the entopeduncular nucleus (EPNSst+) co-release GABA and glutamate in their projection to the lateral habenula, a structure that is key for reward-based learning.

It receives inputs from the limbic system and the basal ganglia and sends outputs to midbrain areas that are involved in the release of dopamine (the substantia nigra pars compacta and ventral ...

We thank Profs. James Martin and Sylvia Arber for generously sharing Pitx2-Cre and tau-mGFP mouse lines, respectively; and Emelie Perland, Thomas Viereckel, and Dr. Carolina Birgner for technical ...