Less than 5% of GI stromal tumors (GISTs) are driven by the loss of the succinate dehydrogenase (SDH) complex, resulting in a pervasive DNA hypermethylation pattern that leads to unique clinical ...

A significant area of study involves succinate dehydrogenase inhibitors (SDHIs), which have shown promise in combating various fungal pathogens. These compounds are designed to target specific ...

(B) Scheme of the protein complexes that form the ETS, showing the mitochondrial membranes in blue and red; NADH dehydrogenase in light green; succinate dehydrogenase in dark green; the complex ...