Deletion of the ‘glial cells missing-2’ gene in mice disrupts development of the parathyroid glands but does not ... Surprisingly, the thymus has been identified as a secondary source of ...

“Our discovery—the regulatory T cell recirculation back to the thymus—promotes repair through ... a novel pathway to regeneration in the gland,” said lead author Andri Lemarquis, MD ...

The researchers were able to show that in the thymus gland of humans and mice not only the epithelial cells but also B cells express and present AQP4 to the T cell precursors. If the B cells were ...