The firm will share new overall survival data from the INAVO120 trial with regulators to support the breast cancer drug's approval.

circularity is defined as 4 · area · π/perimeter 2, which is equal to 1 when the region is perfectly circular. eccentricity denotes the eccentricity of the ellipse with the same second moments as the ...

Trastuzumab emtansine (T-DM1) demonstrates sustained improvement in invasive disease-free survival and reduced the risk for death in human epidermal growth factor receptor 2 (HER2)-positive breast ...

Patients could receive trastuzumab to complete therapy if T-DM1 was discontinued early. 2 Statistical methods and assumptions for the primary analysis have been described in detail 2; the same ...

The development, pharmacology, safety, efficacy, and dosage and administration of trastuzumab are reviewed. The discovery of HER2 gene amplification in up to 30% of women with breast cancer led to ...

received an FDA complete response letter (CRL) on Jan. 3 for its TX-05 BLA, a biosimilar that references Roche AG’s Herceptin (trastuzumab). The CRL cites unnamed issues that need to be addressed by ...

The department has also upgraded its computer systems and marriage registration forms to enable the registration of same-sex marriages promptly once the bill becomes law. “A trial run was carried out ...

eccentricity denotes the eccentricity of the ellipse with the same second moments as the region. The value is equal to 1 when the region is a line and to 0 when the region is a circle. instantaneous ...

Breast cancer is the most commonly diagnosed cancer worldwide. Metal metabolism is pivotal for regulating cell fate and drug sensitivity in breast cancer. Iron and copper are essential metal ions ...

We are working with Guy’s and St. Thomas’ NHS Foundation Trust to produce national standardised SACT regimen-specific consent forms. We want to support clinicians in ensuring all patients are fully ...

Brentuximab vedotin (Adcetris), an ADC made up of an antibody that targets the CD30 antigen (found on lymphocytes), attached to a chemo drug called MMAE Ado-trastuzumab emtansine (Kadcyla ... meaning ...