A century after Down syndrome was first described, scientists discovered that the root cause of this disorder is a condition called trisomy 21. What strides in research have been made since then?

Texas Rangers infielder Jake Burger and his wife, Ashlyn Burger, found out they were having a daughter with Down syndrome. He ...

ARLINGTON, Texas (AP) — Jake Burger will wear No. 21 with the Texas Rangers, a number that has special significance for the first baseman's family after his daughter was born with Down syndrome. The ...

While cell-free fetal DNA screening is useful in identifying potential chromosomal abnormalities, results from it can easily be misunderstood by parents as diagnoses. In the case of an abnormal Down ...

Could science help prevent birth defects? This National Birth Defects Awareness Month, here's the breakthrough every couple ...

The clinical name for Down syndrome is trisomy 21, a condition in which a person is born with an extra chromosome, causing ...

3 Emergency Department, Nottingham University Hospitals NHS Trust, Nottingham, UK 4 Immunology, Nottingham University Hospitals NHS Trust, Nottingham, UK Purpose Children with Trisomy 21 are at ...

The population risk for trisomy 21 is 1 in 700 births but some couples are at a much higher risk owing to parental translocation or mosaicism. We report on the first attempt to carry out ...

Women with a ‘high-chance’ of trisomy 21, 18 or 13 (≥1:150) were offered the choice of no further testing, NIPT or invasive testing, in line with the screening pathway recommended by the UK National ...