Cell types were annotated based on unsupervised clustering, differentially expressed genes, and well-established marker genes for each cluster. To identify major subtypes (trophoblast, stromal_endo, ...

Advanced maternal age (AMA) placenta exhibited premature aging, presumably resulting in trophoblast dysfunction, inadequate placentation. However, the precise reasons and mechanisms of trophoblast ...

Department of Obstetrics, Central People’s Hospital of Zhanjiang, Zhanjiang, Guangdong 524000, China ...

The outer membrane (chorion) and trophoblast layer of the placenta are derived from the trophoectoderm of the blastocyst cells. Other extra-embryonic tissues, including the amnion (inner membrane ...

The European Medicines Agency has recommended three new medicines to treat breast and cervical cancer and ...

Marking the second global approval after Japan, the U.S. FDA has approved Datroway (datopotamab deruxtecan), a trophoblast cell surface antigen 2-directed antibody-drug conjugate (ADC) from Daiichi ...

Fibroblast growth factors (FGFs) signal through FGF receptor tyrosine kinases to regulate a wide range of biological processes during development and adulthood. FGF receptors (FGFRs) are involved ...

It combines a monoclonal antibody, datopotamab, that targets trophoblast cell surface antigen 2 (TROP2), a protein commonly found in high levels on breast cancer cells, with the chemotherapy drug ...

摘要本文针对2024年国内外晚期非小细胞肺癌（NSCLC）取得的临床进展进行回顾。在靶向治疗领域，特别是针对罕见突变的研究，继EGFR、ALK、ROS1等突变后的新靶点，KRAS ...

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1 Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK 2 Department of Obstetrics and Gynaecology, University of Cambridge, Cambridge, UK Correspondence to Clare Teresa ...