A research team has successfully utilized human respiratory organoids (mini-organs) to propagate human rhinovirus C (HRV-C), which had previously been refractory to conventional virus cultivation.

Using a large-scale library of TC organoids they developed, the researchers performed comprehensive comparative analyses of chemo-sensitive and chemo-resistant cells. Their efforts shed light on ...

Organoids are 3D cell culture models that more accurately reflect the structural and functional complexities of organs in vitro than traditional 2D cell culture methods. Generally derived from stem ...

Special artificial placenta tissues, called "trophoblast organoids," have been developed for studying how harmful substances cross the placenta. Researchers are also investigating potentially ...

Brain organoids have shown promise in neurological disease modelling and drug screening. However, their application is limited by several factors, including their heterogeneity and poor ...

Stem-cell differentiation is the process by which a more specialised cell is formed from a stem cell, leading to loss of some of the stem cell's developmental potential. Stem-cell differentiation ...

Organoids allow researchers to mimic complex tissues in vitro, reducing the need for animal models at early research stages. As organoid methods advance, researchers stretch their creativity and use ...

Organoids are 3D multicellular structures derived from stem cells or primary tissues that mimic the architecture and functionality of their tissue of origin. In these specialized structures, various ...