we depicted the landscape of immune cells and identified the trajectory genes involved in the dynamic evolution of CD8+ T cells. Subsequently, three heterogeneous clusters were developed by The Cancer ...

This important study provides solid evidence to support the anti-tumor potential of citalopram, originally an anti-depression drug, in hepatocellular carcinoma (HCC). In addition to their previous ...

Glioblastoma (GBM), an aggressive form of cancer that grows in the brain or spinal cord, occurs at an incidence rate of about 3/100,000 persons in the Unit | Cancer ...

CD8-positive T cells are a critical subpopulation of MHC ... Medulloblastoma in children is a difficult cancer to treat and the immune response to this tumour is not fully understood.

"The anti-correlation of PD-1 and KLRG1 expression in human tumor infiltrating CD8 T cells suggests the potential for combination therapy supra-additive benefits of anti-PD-1 and anti-KLRG1 therapies.

A new research paper was published in Oncotarget's Volume 16 on January 20, 2025, titled "Anti-correlation of KLRG1 and PD-1 expression in human tumor CD8 T cells." The study authored by Dr.

This causes recent findings that blocking the interaction of checkpoint molecule NKG2A in NK and CD8 T cells with HLA-E in tumors is effective in defensing tumors. Interestingly, gut microbiota also ...

Findings indicate that altering glucose metabolism in T cells boosts their therapeutic potential against melanoma, paving the way for improved immunotherapies.

Pathogen-fighting immune cells called tissue-resident memory CD8 T cells (TRM cells ... immune cells may be key players in future cancer immunotherapies that target tumors in specific organs.