Following the discovery of inhibitory KIR and the understanding that they play a role in preventing NK cell killing of self MHC I-expressing tumor cells, investigators began to research the ...

4Research Unit of NK Cell Study, Chinese Academy of Medical Sciences ... 6Department of Medical Oncology, Fudan University Shanghai Cancer Center, Shanghai, China. 7Department of Oncology, Shanghai ...

Introduction: Ovarian cancer (OC) is the sixth most common malignancy in women and the poor 5-year survival emphasises the need for novel therapies. NK cells play an important role in the control of ...

One important consideration in multi-stage cell design is how to determine the appropriate transistor sizes for the input stage while the output stage drive is increased. For example, consider an 8x ...

Korean researchers have developed a technology that treats colon cancer by converting cancer cells into a state resembling normal colon cells. Listen to Story Researchers in South Korea have developed ...

Scientists found that healthy women can carry genetic changes in their breast cells that are thought to be characteristic of invasive breast cancer. Most cancer cells have too many or too few ...

The study, published today in the journal Nature Immunology, focused on chimeric antigen receptor (CAR)-T cells, an effective therapy against cancer, especially leukemia and lymphoma. T cells, a ...

However, the impact of complex tumor-infiltrating immune cell profiles on responses to immune checkpoint inhibitors is not fully understood; limited evidence has yielded contradictory findings.

Coley’s reasoning was that infection could trigger the immune system to fight cancer. That idea ... So-called natural killer cells and macrophages can also identify and destroy cancerous ...

The goal of traditional cancer treatments is to destroy cancer cells. Although this approach is often successful, it has two major drawbacks: the possibility that cancer cells will become resistant ...