Monosodium urate crystals dissolve and are eliminated from joints and soft tissues as serum uric acid levels drop below its saturating point (400 μmol/l). Time to crystal clearance relates to ...

If gout itself contributes an additional cardiovascular risk, is this effect explained by the inflammatory state caused by the deposition of monosodium urate crystals? During an acute attack of ...

A recent study by researchers from the University of California San Diego and collaborators has uncovered a new molecular pathway responsible for gout and its progression to joint tissue damage. The ...

No gout attack has occurred since the sixth infusion ... Numerous negatively birefringent needle-shaped monosodium urate crystals are detected by compensated polarized-light microscopy (original ...

Gout is a type of inflammatory arthritis that develops when high uric acid levels in the body form urate crystals in joints ...

Among patients with gout in the US, Black individuals and those living in the South were associated with reduced adherence to allopurinol.

Gout is a prevalent metabolic disorder characterized by urate crystal accumulation in joints, leading to acute arthritis and tophi formation. Despite advancements in management, the incidence and ...

Perspective from David A. McLain, MD, MACR, FACP, FRCP Colchicine for gout flare prophylaxis reduces the risk for cardiovascular events among patients initiating urate-lowering therapy ...

Uric acid-induced kidney damage can occur through various mechanisms, including the activation of pro-inflammatory pathways and the accumulation of urate crystals in the kidney tubules ...

Gout is a condition when urate, a substance in the body, builds up and forms needle-shaped crystals in your joints. This leads to pain, swelling, redness, and changes in the movement and use of ...