we have created several important VEGF peptide mimics that block ligand (VEGF)–receptor (VEGFR-2) interactions, thereby inhibiting angiogenesis. A combination approach targeting these two ...

Sprouting, migration and proliferation of lymphatic endothelial cells is regulated by VEGFC and the VEGF receptor-3 (VEGFR3). Arteriovenous identity is controlled by haemodynamic factors and ...

The HER family receptors form a signaling network that contributes to cancer progression. Angiogenesis plays a major role in cancer and VEGF-targeted agents have been shown to be useful in ...