A most remarkable feature of HIV is its ability to replicate continuously and unrelentingly despite apparently strong antibody and cytotoxic T-lymphocyte (CTL) responses. Here, Ronald Desrosiers ...

By Dr. Priyom Bose, Ph.D. A recent Nature Immunology study explores the cellular and molecular adaptations associated with human secondary lymphoid tissue in adults during viral infection. Study: ...

Cytotoxic T lymphocytes (CTLs) are considered to play ... still contribute to a reduced viral load. The implications of current knowledge on HIV-specific cellular immunity for vaccine development ...

In the case of viral exanthems, the target is viral antigens expressed on the surface of keratinocytes and recognized as foreign by lymphocytes, particularly of the CD8 subtype. Similarly in SJS ...