Objectives Bone destruction in rheumatoid arthritis is mediated by osteoclasts (OC), which are derived from precursor cells of the myeloid lineage. The role of the two monocyte subsets, classical ...

The manuscript addresses the 3D chromatin architecture in monocytes from patients with alcohol-associated hepatitis and its relationship to enhanced transcription of innate immune genes. While the ...

Monocytes and macrophages are myeloid cells that have important innate immune functions. Macrophages reside in tissues and respond to infection by producing inflammatory mediators and engulfing ...

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zju.edu.cn Objective Macrophages are among the most abundant cells in the colon tumour microenvironment, and there is a close relationship among monocytes, macrophages and the gut microbiota.

Meanwhile, similar results were observed in multiple sensitivity analyses. Compared with carotid color ultrasonography, monocyte to high‐density lipoprotein ratio, a biomarker calculated by blood ...

Wild type (WT) Balb/c mice were purchased from Harlan and Janvier. αMyHC-TCR transgenic mice (TCR-M) on Balb/c background were previously described (35). Irf4 fl/fl.Cd11cCre mice were backcrossed onto ...

Starting from the hypothesis that immune cells promptly respond to harmful stimuli, we used peripheral blood monocytes in order to characterise a distinct gene expression profile and to evaluate its ...

Neither is the idea of an inexperienced Batman making mistakes. But what makes this particular turn in Absolute Batman #5 noteworthy is this is less a matter of the villain getting the upper hand ...

We find that JEV causes HMGB1 release from BMECs while increasing adhesion molecules. Recombinant HMGB1 enhances leukocyte-endothelium adhesion, facilitating JEV-infected monocyte transmigration ...