Two new compounds may be able to treat retinitis pigmentosa, a group of inherited eye diseases that cause blindness. The compounds were identified using a virtual screening approach.

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Vitamin A is a key component in rhodopsin, a light-sensitive protein that helps in producing pigments in the retina, which help with vision in low light areas.

AN eight-year-old child is now permanently blind after his picky eating habits left him severely malnourished. The schoolboy, from Malaysia, lived on nothing but chicken nuggets, sausages, and ...

(A,B) Rod photoreceptors were evaluated by immunostaining of REEP6 and rhodopsin (Rho) at P70. The representative images were taken from dorsal retina, 1000 µm away from the optic nerve. The scale bar ...

In retinitis pigmentosa, the retina protein rhodopsin is often misfolded due to genetic mutations, causing retinal cells to die off and leading to progressive blindness. Small molecules to correct ...

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In their paper, titled “Discovery of non-retinoid compounds that suppress the pathogenic effects of misfolded rhodopsin in a mouse model of retinitis pigmentosa,” the team concluded ...

In retinitis pigmentosa, the retina protein rhodopsin is often misfolded due to genetic mutations, causing retinal cells to die off and leading to progressive blindness. Small molecules to correct ...

Treatment with bioavailable small-molecule pharmacochaperones targeting the visual receptor rhodopsin offers a promising approach to prevent retinal photoreceptor degeneration caused by inherited ...

Treatment with bioavailable small-molecule pharmacochaperones targeting the visual receptor rhodopsin offers a promising approach to prevent retinal photoreceptor degeneration caused by inherited ...