Newly generated human embryonic stem cell‐derived atrial‐like cardiomyocytes resemble human atrial cardiomyocytes and prove to be a valuable model for pre‐clinical drug screenings to identify ...

Zebrafish protein unlocks dormant genes for heart repair Date: January 2, 2025 Source: Hubrecht Institute Summary: Researchers have successfully repaired damaged mouse hearts using a protein from ...

The paper presents a streamlined new approach for functional validation of genes known to underlie fragile bone disorders in a relatively high throughput, using CRISPR-mediated knockouts and a number ...

However, the cost and time required to establish mouse animal models are high. The existing zebrafish model can solve this problem well. Zebrafish is an animal model with great application prospects ...

Research Center for Environmental Quality Management, Graduate School of Engineering, Kyoto University, Otsu, Shiga 520-0811, Japan Key Laboratory of Industrial Ecology and Environmental Engineering ...

Abstract: Zebrafish have emerged as a powerful model organism in cardiovascular disease research. Accurately identifying zebrafish blood vessels and evaluating blood flow velocity without injury has a ...

This study reported that cold exposure induced mRNA expression of genes related to lipid metabolism in the paraventricular nucleus of the hypothalamus (PVH). The authors provide useful data ...

Examples of the animals are roundworms (Caenorhabditis elegans), fruit flies (Drosophila melanogaster), zebrafish (Danio rerio), rodents (Mus musculus and Rattus norvegicus), and non-human primates ...

The best treatment strategy for patients with apical aneurysms remains unclear, and some clinicians have recommended treatment with an implantable cardioverter defibrillator or catheter ablation for ...

PA-LA indicates pulmonary artery-left atrium; PH, pulmonary hypertension; RV, right ventricle; VA-ECMO, venoarterial extracorporeal membrane oxygenation; and VV-ECMO, venovenous extracorporeal ...