Although obese individuals are at greater risk of diabetes, high blood pressure or high cholesterol, not all obese people ...

As many as 40% of Americans are obese, putting them at an increased risk for high blood pressure, diabetes, stroke, heart ...

Researchers have discovered significant differences in gene expression in adipose tissue, more commonly known as fat.

Obesity is an increasingly prevalent human condition in developed societies. Despite major progress in the understanding of the molecular mechanisms leading to obesity, no safe and effective ...

Both conditions promote the development of associated metabolic diseases such as insulin resistance. The visceral adipose tissue (VAT) is a site that becomes dysfunctional during obesity and aging, ...

Body weight and body mass index alone are not enough to predict whether someone will develop a metabolic disease. A new atlas of cells in fat tissue could help to explain why some overweight people ...

Adrenomedullin (ADM) inhibits endothelial insulin signaling, contributing to obesity-associated insulin resistance, according ...

The study presents important findings on inositol-requiring enzyme (IRE1α) inhibition on diet-induced obesity (overnutrition) and insulin resistance where IRE1α inhibition enhances thermogenesis and ...

Researchers investigate the underlying mechanisms of endothelial insulin resistance involved in obesity-associated diabetes.