The trial compared Moderna's MRNA-4157/V940 vaccine given alongside Merck & Co's cancer immunotherapy Keytruda (pembrolizumab) to Keytruda alone in patients with the skin cancer melanoma.

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Gene expression is the generation of a functional ... the machinery and mechanisms involved in the control of cytoplasmic mRNA decay and comment on implications for the design of therapeutic ...

Discover the top genomics startups revolutionizing genome sequencing technologies to enhance disease prevention and treatment ...

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Jan. 23, 2025 — Scientists have shown that specialized cells involved in how the body responds to insulin are activated in the brain after exercise, suggesting that physical activity may ...

This paper addresses the important question of quantifying epistasis patterns, which affect the predictability of evolution, by reanalyzing a recently published combinatorial deep mutational scan ...

All data generated or analysed during this study including Macro for automated fluorescent intensity measurement are included in the manuscript and supporting file; Source Data files have been ...

Jan. 17, 2025 — Cutting-edge fluorescent cholesterol probes now enable scientists to visualize cholesterol movement and distribution in live cells with unprecedented detail. By combining ...