2 Its specificity for RA is thus limited. Here we describe the mRNA and protein expression of PAD enzymes in monocytes and macrophages, as well as in synovial fluid mononuclear cells (SFMCs). Possible ...

The LNP-mRNA modality is a novel approach that uses lipid nanoparticles to deliver messenger RNA into cells. The mRNA acts as ...

After incubation, the samples were collected and directly frozen in liquid nitrogen for succeeding ... III and moderately decreased at stage IV without significant difference (Figures 2A,B). By ...

The primer sequences of each gene were listed in Table 1. The relative gene expression level was determined by the 2 −ΔΔCT method, using GAPDH as an internal reference. DNA extraction was performed ...

In the present study, we tested the hypothesis that exposure of newborn mice to sublethal hyperoxia would alter lung development and expressions ... of FGFR-3 and FGFR-4 mRNA were greater at ...

mRNA expression of several genes was compared between surgical liver samples and postmortem liver samples. Semiquantitative RT-PCR of oncogene Ets-1, one of the extracellular matrix components of the ...

An innovative organoid model mirrors the pancreas' complexity, generating all three key cell types to explore development and ...

ETH47 administration also activated the mRNA expression of antiviral interferon-stimulated genes (ISGs) in nasal brush samples. These findings confirm ETH47’s pharmacodynamic activity and ...

From being a promising yet underexplored approach in the 1990s, mRNA therapeutics have evolved dramatically. The discovery of ...

Ethris GmbH, a leading biotechnology company pioneering next-generation RNA therapeutics and vaccines, today announced promising topline data from the completed Phase 1 clinical trial of its lead mRNA ...

Keloids are fibrotic scars that extend beyond the boundaries of the original wound, often causing physical disfigurement and emotional distress. These scars are driven by an overproduction of ...