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RNA is generally single-stranded, as DNA is transcribed by RNA polymerases into mRNA (messenger RNA ... by complementary pairing between nucleotide bases. Rapid detection of diverse biomarkers ...

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“Larger mRNA-based therapeutics are synthesised by in vitro transcription, which is not amenable to extensive nucleotide modifications ... Building a base When asked about the progress Liberate ...

RNAFold further enhances its predictions with a detailed entropy analysis, using overlapping curves for MFE, probable folding pathways, and Centroid structures to illustrate structural variability at ...

Through base editing, drugs replace single nucleotide in the DNA strand with another, without making double-strand breaks (DSBs) in the gene. Other CRISPR-based therapies generate a DSB at a ...

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Moderna's mRNA technology gained rapid validation as sales of its covid vaccine soared in 2021 and 2022, but we think the firm has yet to secure a narrow economic moat around its business ...

But scientists at Moderna are in the late stages of testing what could be the first such shot, using mRNA technology against the virus. Here’s what to know about norovirus and where things stand ...