This is a useful study that seeks to address the role of the TET family of DNA demethylation enzymes in pancreatic beta cell senescence in the context of type 2 diabetes (T2DM). Although the concepts ...
Once administered, the naked mRNA is taken up by cells, including DCs, through endocytosis or direct membrane fusion (Hasan et al., 2023). After entering the cytoplasm, the mRNA is translated into the ...
Wall Street is off to a volatile start in 2025, with investors stepping on the sell pedal after last week's jobs data, followed by a sharp about-face in sentiment following Wednesday's consumer ...
Moderna's mRNA technology gained rapid validation as sales of its covid vaccine soared in 2021 and 2022, but we think the firm has yet to secure a narrow economic moat around its business ...
The current human tissue-based study provides convincing evidence correlating hippocampal expressions of RNA guanine-rich G-quadruplexes with aging and with Alzheimer's Disease presence and severity.
Melissa Moore helped usher in the first mRNA medicines, but the former Moderna executive thinks there’s still a lot of room for improvement.