A novel mTORC1 inhibitor Hyperactivation of mechanistic target of rapamycin complex 1 (mTORC1) signaling pathways is common feature of the diseases of aging. mTORC1 inhibition is a promising treatment ...
However, long-term use may impair mTORC2 assembly and functioning. [9] Although less is known about this complex than mTORC1, two major functions have been attributed to mTORC2: regulation and ...
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