Combination therapy with oral or inhaled treprostinil may benefit patients with pulmonary arterial hypertension and cardiovascular comorbidities.

BNP是一种心脏分泌的肽类激素，其主要使命是调节体内的水盐平衡并抑制心脏的压力。然而，仅凭BNP水平的高低来判断一个人是否患有心衰，可能会导致错误的诊断。许多研究，包括2019年的《传感器》期刊，指出BNP水平的变化可以受多种因素的影响，如年龄、体重、肾功能等。因此，临床医生不能仅只依赖BNP数据，必须结合其他临床指标全面评估患者的心脏健康状况。

Obesity influences the thresholds, but even in nonobese patients with dyspnea, optimal cutoffs may be lower than recommended.

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