Loading Nexus. NEXUS2 works with any DAW that supports the VSTi or Audio Unit plug-in formats, and with Pro Tools 7.3 or greater (RTAS and AAX). To use NEXUS2, load it into a track in your DAW just like you would any other virtual instrument. NEXUS2 receives on all 16 MIDI channels simultaneously, so there's no need to set a MIDI channel.