Organogermanium chemistry is the science of chemical species containing one or more C – Ge bonds. Germanium shares group 14 in the periodic table with carbon, silicon, tin and lead. Historically, organogermanes are considered as nucleophiles and the reactivity of them is between that of organosilicon and organotin compounds.

Organic germanium is known to possess various biological and pharmacological activities, and is often used in medicine for purposes such as anti-tumor, antiviral, antibacterial, antioxidant, immune regulation, production of hypoglycemic lipids, scavenging free radicals, and stimulating the hematopoietic system . There has been increasing ...

Abstract. Organogermanium, especially poly‐trans‐[(2‐carboxyethyl)germasesquioxane] (Ge‐132), has been known to enhance immune‐modulatory activities.However, the in vivo and in vitro evidence accumulated over the last 20 years reveals that Ge‐132 has unique but underappreciated multi‐functional properties that have a potential positive effect for the …

Germanium's anti-viral and immunological properties, including the induction of interferon, macrophages, T-suppressor cells and augmentation of natural killer cell activity, suggest its possible efficacy in treating and/or preventing AIDS.

1988年7月1日 · This report reviews the literature, with particular emphasis upon organic germanium's therapeutic effects in cancer, which appear to be mediated by immuno-modulation, features which suggest its possible role in the treatment and/or prevention of AIDS.

1988年7月1日 · Clinical trials and use in private practices for more than a decade have demonstrated Germanium's efficacy in treating a wide range of serious afflictions, including cancer, arthritis and senile osteoporosis.

2023年3月15日 · Several organogermanium compounds were studied for their potential medical use. However, most were not suitable for medical development. In this chapter, we discuss bioactive organogermanium compounds with a particular focus on Asaigermanium. The erythropoietic action of germanium dioxide II.

Organogermanium compounds are a class of chemical compounds that contain germanium atoms bonded to organic groups. These compounds have attracted significant interest due to their unique properties and potential applications in areas such as thermochromism, absorption in the UV/visible spectral region, conductivity, and luminescence.

2023年6月1日 · The most-studied organic germanium compound is bis (carboxy ethylgermanium) sesquioxide (Ge-132). Its synthesis is carried out by the addition of trichlorogermane (HgeCl 3) to acrylic acid to produce 3- (trichlorogermyl)propanoic acid, followed by the hydrolysis thereof.

2019年9月5日 · Germanium (Ge) is a widely distributed but rare element on earth. Organic germanium is the most widely used form of germanium. Compared to the common metal (mercury, cadmium, lead, etc.), organic germanium is much less toxic to humans than others.