2017年7月26日 · A leukocyte alkaline phosphatase (LAP) test is a laboratory test that can be conducted on a sample of your blood. Your doctor can order it to measure the amount of alkaline phosphatase, a...

CML usually presents with a marked leukocytosis (the WBC is often over 100,000), with a left shift all the way back to myeloblasts (though there are relatively few myeloblasts around).

Leukocyte alkaline phosphatase is found within mature white blood cells. White blood cell levels of LAP can help in the diagnosis of certain conditions. [76]

2005年1月14日 · The leukocyte alkaine phosphatase (LAP) score is often used in patients with an elevated WBC to differentiate a reactive process from chronic myelogenous leukemia.The score in the latter is low while it is within the normal reference range or elevated in the former condition.

2007年11月16日 · Leukocyte Alkaline Phosphatase (LAP) Score is valuable in the work-up of certain hematological diseases. Most notably, the score is decreased in Chronic Myelogenous Leukemia and Paraoxysmal Nocturnal Hemaglobinurea but increased in leukemoid reaction to infection and Polycythemia Vera.

An alkaline phosphatase (ALP) test measures the amount of ALP in your blood. Although ALP exists throughout your body, the two main sources of ALP in your blood are your liver and bones. High levels of ALP may indicate liver disease or certain bone disorders, but an ALP test alone cannot diagnose a condition.

Leukocyte alkaline phosphatase (LAP) / Neutrophil alkaline phosphatase (NAP) stain stands as a valuable diagnostic tool, offering insights into the functionality of neutrophils, a critical component of the immune system.

2019年6月11日 · Learn in-depth information on Leukocyte Alkaline Phosphatase Blood Test, on why the laboratory test is performed, specimen collected, the significance of the results, and its use in diagnosing medical conditions.

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Highest concentra-tions are in liver and bone, but the enzyme is present in lesser amounts in placenta, kidney, intestines, and leukocytes. Increased concentrations of alka-line phosphatase are derived from tis-sues that are either functionally dis-turbed (obstructed liver) or greatly stimulated (growing bone).