A megakaryocyte (from mega- 'large' karyo- 'cell nucleus' and -cyte 'cell') is a large bone marrow cell with a lobated nucleus that produces blood platelets (thrombocytes), which are necessary …

2023年10月30日 · Megakaryocytes are a special type of bone marrow cells that give rise to thrombocytes (platelets). These cells are large and measure about 50–150 µm in diameter …

Megakaryocytes are rare cells found in the bone marrow, responsible for the everyday production and release of millions of platelets into the bloodstream.

Megakaryocytes are large polyploid cells most commonly identified in bone marrow. Egress via sinusoids enables migration to the pulmonary capillary bed, where elaboration of platelets can …

Single-cell RNA sequencing studies have revealed transcriptional heterogeneity within the megakaryocytic lineage and the identified unique subsets. In this review, we discuss the …

2022年1月27日 · Platelets are formed from megakaryocytes (MKs), their precursor cells, which reside predominantly in the bone marrow (BM). MKs are large hematopoietic cells, making up …

Megakaryocytes are highly specialized large nuclear cells (50–100μm in diameter) that differentiate to produce platelets. You might find these chapters and articles relevant to this …

2023年9月7日 · In this review, we discuss current knowledge about megakaryocyte diversity, with a focus on possible megakaryocyte subpopulations (thrombopoietic, immune, niche support, …

This topic reviews the biology of megakaryocytes and the mechanisms of platelet production in the bone marrow. Separate topics discuss the biology of hematopoietic stem cells (HSCs), …

megakaryocyte A very large cell native to the bone marrow which is the precursor of platelets and the largest (40–100 µm in diameter) normal nucleated haematopoietic cell in the marrow. …