ABCA1 gene - MedlinePlus
The ABCA1 gene belongs to a group of genes called the ATP-binding cassette family, which provides instructions for making proteins that transport molecules across cell membranes. …
ABCA1 Gene - GeneCards | ABCA1 Protein | ABCA1 Antibody
2024年12月24日 · ABCA1 (ATP Binding Cassette Subfamily A Member 1) is a Protein Coding gene. Diseases associated with ABCA1 include Tangier Disease and …
The Role of the ATP-Binding Cassette A1 (ABCA1) in Human Disease
Pancreatic β-cell specific Abca1 KO mice (Abca1-P/-P) showed age-related and gene-dose-dependent accumulation of cholesterol in β-cells. In addition, these mice showed significantly …
Is ABCA1 a lipid transfer protein? - PMC - PubMed Central (PMC)
ABCA1 functions as a lipid transporter because it mediates the transfer of cellular phospholipid (PL) and free (unesterified) cholesterol (FC) to apoA-I and related proteins present in the …
ABCA1 ATP binding cassette subfamily A member 1 [ (human)]
2025年1月4日 · ABCA1 R219K polymorphism is a protective factor of coronary heart disease in Asians, but not in Caucasians. ABCA1 impacts athero-thrombotic risk and has a role in …
ABCA1 and metabolic syndrome; a review of the ABCA1 role in …
ATP-binding cassette transporter A1 (ABCA1) is an integral cell-membrane protein that mediates the rate-limiting step of high density lipoprotein (HDL) biogenesis and suppression of …
Complete genomic sequence of the human ABCA1 gene: Analysis …
The ABCA1 gene, a member of the ATP-binding cassette A (ABCA1) transporter superfamily, encodes a membrane protein that facilitates the cellular efflux of cholesterol and …
Role of ABCA1 in Cardiovascular Disease - MDPI
2022年6月20日 · Cholesterol homeostasis plays a significant role in cardiovascular disease. Previous studies have indicated that ATP-binding cassette transporter A1 (ABCA1) is one of …
Structure of the Human Lipid Exporter ABCA1 - Cell Press
2017年6月15日 · ABCA1, an ATP-binding cassette (ABC) subfamily A exporter, mediates the cellular efflux of phospholipids and cholesterol to the extracellular acceptor apolipoprotein A-I …
Regulation of ABCA1 functions by signaling pathways - PubMed
ABCA1 exports cholesterol and phospholipids from cells by multiple steps that involve forming cell surface lipid domains, binding of apolipoproteins to ABCA1, activating signaling pathways, and …
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