Dexrazoxane - Wikipedia
Currently, the only FDA and EMA approved cardioprotective treatment for anthracycline cardioprotection is dexrazoxane, which provides effective primary cardioprotection against anthracycline-induced cardiotoxicity without reducing anthracycline activity and without enhancing secondary malignancies.
Dexrazoxane Uses, Side Effects & Warnings - Drugs.com
2023年8月9日 · Dexrazoxane is used to protect the heart and other tissues from harmful side effects caused by certain cancer medications. The Totect brand of dexrazoxane is used in men or women to treat a condition called extravasation (es-TRA-va-ZAY-shun).
Dexrazoxane - StatPearls - NCBI Bookshelf
2023年7月17日 · Dexrazoxane is a medication used in the management and treatment of anthracycline-induced cardiotoxicity and extravasation injuries. It is in the class of medications known as cardioprotectants.
Dexrazoxane Hydrochloride - NCI - National Cancer Institute
Dexrazoxane hydrochloride is approved to treat severe side effects caused by certain types of chemotherapy. It is used to treat the following: Cardiac (heart) side effects caused by doxorubicin hydrochloride in women being treated for metastatic breast cancer.
Dexrazoxane: Uses, Interactions, Mechanism of Action
Dexrazoxane is a cardioprotective agent for use in conjunction with doxorubicin indicated for reducing the incidence and severity of cardiomyopathy associated with doxorubicin administration in women with metastatic breast cancer who have received a cumulative doxorubicin dose.
Dexrazoxane (intravenous route) - Mayo Clinic
2024年1月31日 · Dexrazoxane is used to help prevent heart problems (eg, cardiomyopathy) in women receiving doxorubicin for breast cancer. Dexrazoxane injection is used to treat tissue damage caused by the leakage of certain cancer medicines from the injection site.
Dexrazoxane for the treatment of chemotherapy-related side …
Presently, dexrazoxane is licensed in many parts of the world for two different indications: prevention of cardiotoxicity from anthracycline-based chemotherapy, and prevention of tissue injuries after extravasation of anthracyclines.
Totect (dexrazoxane) Uses, Dosage, Side Effects - Drugs.com
2023年8月23日 · Totect is used to protect the heart and other tissues from harmful side effects caused by certain cancer medications. Totect is used in men or women to treat a condition called extravasation (es-TRA-va-ZAY-shun). Extravasation happens when an injected medicine escapes from the blood vessels and circulates into tissues in the body.
Dexrazoxane for the Prevention of Cardiac Toxicity and …
Dexrazoxane is the first and only agent that has been demonstrated to block the development of anthracycline-induced cardiac toxicity in the clinic; controlled clinical trials have proven that this drug dramatically reduces the incidence of cardiac toxicity in patients with breast cancer without significantly altering the antitumor activity of ...
Dexrazoxane: Dosage, Mechanism/Onset of Action, Half-Life
2020年2月17日 · Includes Dexrazoxane indications, dosage/administration, pharmacology, mechanism/onset/duration of action, half-life, dosage forms, interactions, warnings, adverse reactions, off-label uses and more.