The fragment crystallizable region (Fc region) is the tail region of an antibody that interacts with cell surface receptors called Fc receptors and some proteins of the complement system. This …

The Fc region, or crystallizable fragment, is a portion of an antibody molecule that does not directly bind to antigen. It is responsible for the effector functions of the antibody, such as …

Each V domain can be split into three regions of sequence variability, termed the complementarity determining regions, or CDRs, and four regions of relatively constant sequence termed the …

In immunology, an Fc receptor is a protein found on the surface of certain cells – including, among others, B lymphocytes, follicular dendritic cells, natural killer cells, macrophages, neutrophils, …

Antibodies all have the same basic structure consisting of two heavy and two light chains forming two Fab arms containing identical domains at either end attached by a flexible hinge region to …

Fragment crystallizable region (Fc region) is the tail region of an antibody that interacts with cell surface receptors called Fc receptors and some proteins of the complement system. You …

The Fc region is the tail part of an antibody that interacts with cell surface receptors and complement proteins. It plays a crucial role in modulating immune responses.

The fc region of an antibody is essential for its interaction with various immune cells. This region binds to specific Fc receptors on immune cells like macrophages and natural killer cells, …

Fc engineering aims to enhance the effector functions or half-life of therapeutic antibodies by modifying their Fc regions. Recent advances in the Fc engineering of modern therapeutic …

It has been discovered that glycosylation of the IgG’s Fc region critically affects Fc binding capacities by FcγR or complement. Alterations of the glycosylation pattern might therefore …