LA-ICP-MS (Laser Ablation Inductively Coupled Plasma Mass Spectrometry) is a powerful analytical technology that enables highly sensitive elemental and isotopic analysis to be performed directly on solid samples.

Laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) is a powerful technique for the elemental analysis of a wide variety of materials encountered in forensic casework.

Laser Ablation (LA) is a solid sampling technique that uses short pulses of high intensity light to convert a solid sample directly into an aerosol, which is transferred into ICP ion source for analysis, typically by inductively coupled plasma mass spectrometry (ICP-MS).

Laser Ablation Inductively Coupled Plasma Mass Spectrometry (LA-ICP-MS) is an analytical technique that uses direct micro-scale sampling to provide high precision elemental and stable isotope analyses of solid materials.

Laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) enables identification and comparison of physical evidence, discriminating elemental and isotopic differences at the part per billion (ppb) level.

Laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) has become one of the most widely applied techniques for direct solid analysis. This article describes the working principle, instrumentation, fundamental aspects of the ablation process, quantification strategies, and typical figures of merit of this technique.

Agilent ICP-MS systems connect seamlessly to all leading Laser Ablation (LA) systems to provide high performance LA-ICP-MS analysis of solid samples. LA-ICP-MS is highly flexible, supporting high resolution imaging, micron-scale in-situ elemental and isotopic analysis, quantification of bulk composition, and precise depth profiling.