Nalbuphine is a semisynthetic mixed agonist/antagonist opioid modulator of the phenanthrene or morphinan series. It is structurally related to the widely used opioid antagonists naloxone and naltrexone, and to the potent opioid analgesic oxymorphone. Nalbuphine binds with high affinity to the MOR and KOR, [9] and has relatively low affinity for ...

2023年5月1日 · This activity outlines the indications, mechanism of action, methods of administration, significant adverse effects, contraindications, monitoring, and toxicity of nalbuphine, so providers can direct patient therapy to optimal outcomes when pain …

Nalbuphine is an opioid pain medication that is used to treat moderate to severe pain. It is also used for treating pain just after surgery or childbirth. Nalbuphine may also be used for purposes not listed in this medication guide.

Nalbuphine injection is used is used to relieve severe pain in people who are expected to need an opioid pain medication and who cannot be treated with other pain medications. It is also used with other medications and anesthesic agents before, during, and …

2024年12月10日 · Nalbuphine package insert / prescribing information for healthcare professionals. Includes: indications, dosage, adverse reactions and pharmacology.

Nalbuphine reference guide for safe and effective use from the American Society of Health-System Pharmacists (AHFS DI).

2020年2月17日 · Includes Nalbuphine indications, dosage/administration, pharmacology, mechanism/onset/duration of action, half-life, dosage forms, interactions, warnings, adverse reactions, off-label uses and more.

Nalbuphine belongs to the group of medicines called narcotic analgesics (pain medicines). It acts on the central nervous system (CNS) to relieve pain. When a nalbuphine injection is used for a long time, it may become habit-forming, causing mental or physical dependence.

Nalbuphine is an opioid agonist-antagonist used to treat pain, for pre and postoperative analgesia, and for analgesia in labor and delivery. A narcotic used as a pain medication. It appears to be an agonist at kappa opioid receptors and an antagonist or partial agonist at mu opioid receptors.

2024年1月10日 · Nalbuphine hydrochloride is a synthetic opioid agonist-antagonist analgesic of the phenanthrene series. It is chemically related to both the widely used opioid antagonist, naloxone, and the potent opioid analgesic, oxymorphone. Chemically nalbuphine hydrochloride is 17-(cyclobutylmethyl)-4,5α- epoxymorphinan-3,6α,14-triol hydrochloride.