Quinazoline is an organic compound with the formula C 8 H 6 N 2. It is an aromatic heterocycle with a bicyclic structure consisting of two fused six-membered aromatic rings, a benzene ring …

Quinazolines are nitrogen-containing heterocycles that consist of a benzene ring fused with a pyrimidine ring. Quinazolinones, oxidized quinazolines, are promising compounds with a wide …

2018年5月10日 · This review gives detailed attention on in vitro and in vivo pharmacological activities of quinazoline and its analogs in the perspective of drug discovery and its development.

Quinazolines and quinazolinone are a large class of biologically active compounds that exhibited broad spectrum of biological activities such as anti-HIV, anticancer, antifungal, antibacterial, …

2018年5月10日 · Quinazoline (1,3-diazanaphthalene) is a nitrogen containing heterocyclic compound illustrated by a double-ring structure that contains a benzene ring system fused to …

Quinazoline (1,3-diazanaphthalene; 1) is a moiety made up of two condensed six-membered aromatic rings, a pyrimidine ring, and a benzene ring (Wang and Gao, 2013). It is yellow and …

Quinazoline is a mancude organic heterobicyclic parent that is naphthalene in which the carbon atoms at positions 1 and 3 have been replaced by nitrogen atoms. It is a mancude organic …

Quinazoline is a bicyclic heterocycle with benzene ring fused with pyrimidine nucleus. Quinazoline has contributed to many pharmacological profiles such as anti-cancer, anti inflammatory [58], …

2022年12月2日 · The developing understanding of quinazoline derivatives and their biological targets presents opportunities for the discovery of novel therapeutics. This review represents …

Proposed anticancer mechanisms for quinazoline derivatives include: 1) inhibition of the DNA repair enzyme system, 2) inhibition of EGFR, 3) thymidylate enzyme inhibition and 4) inhibitory …