2019年10月19日 · • Select a -lactam from a different class with a dissimilar R1/R2 side chain (clear box) Antimicrobial Stewardship Program, pager 55955 • The R1 side chain is the major factor for cross-reactivity due to antibody recognition between cephalosporins and penicillins.
2023年6月4日 · Beta-lactam antibiotics are used in the management and treatment of bacterial infections. This activity will highlight the mechanism of action, adverse event profile, and other key factors (e.g., off-label uses, dosing, pharmacodynamics, pharmacokinetics, monitoring, relevant interactions) pertinent for members of an interprofessional ...
2023年2月2日 · The chart below is a reference for which beta-lactams share similar side chains. This may be used to guide clinical decisions surrounding which antibiotics are appropriate to use in patients with specific beta-lactam allergies.
Also known as beta-lactams, this class of antibiotics prevents growth of the bacterial cell wall and are classified as bactericidal. This class includes 5 different groups: aminopenicillins, antipseudomonal penicillins, beta-lactamase inhibitors, natural penicillins, and penicillinase resistant penicillins. Generic Brand Name Examples
This is a list of common β-lactam antibiotics—both administered drugs and those not in clinical use—organized by structural class. Antibiotics are listed alphabetically within their class or subclass by their nonproprietary name.
Beta-lactamases are a diverse class of enzymes produced by bacteria that break open the beta-lactam ring, inactivating the beta-lactam antibiotic. Some beta-lactamases are encoded on mobile genetic elements (eg, plasmids); others are encoded on chromosomes.
The NM -lactam cross-reactivity side chain chart is a guide and should be used with the NM -lactam Allergy Risk Assessment and Clinical Pathway for Outpatients or Non-Critically Ill Inpatients when assessing the decision to drug challenge with a -lactam.
The R1 side chain is the major factor for cross-reactivity due to antibody recognition between cephalosporins and penicillins. reaction likely. C reaction less likely. Similar R1 or R2 side chain.
Antibiotic classifications and subclassifications: This classification categorizes antibiotics into groups such as beta-lactam antibiotics, penicillins, cephalosporins, macrolides, and more. Each group is further divided to reflect specific characteristics and uses.