Mitochondrial fusion - Wikipedia
Mitochondrial fusion enables content mixing within a mitochondrial population, thereby preventing permanent loss of essential components. Cells with reduced mitochondrial fusion show a subpopulation of mitochondria that lack mtDNA nucleoids.
Mitochondrial fusion and fission in cell life and death
2010年11月23日 · Reports the identification of the first known mediator of mitochondrial fusion and, at the same time, describes the role of fusion in remodelling of mitochondria during spermatogenesis.
Mitochondrial fission and fusion - PMC - PubMed Central (PMC)
In the present chapter we discuss the mechanisms behind mitochondrial fission and fusion, and discuss the implications of changes in organelle morphology during the life of a cell. In addition to their classic role as generators of ATP, mitochondria are central to several vital cellular functions.
Mitochondria, Fusion, Division | Learn Science at Scitable - Nature
Mitochondrial fusion is the physical merging of the outer and then the inner mitochondrial membranes of two originally distinct mitochondria.
Mitochondrial Fission, Fusion, and Stress - PMC
Mitochondrial fission and fusion play critical roles in maintaining functional mitochondria when cells experience metabolic or environmental stresses. Fusion helps mitigate stress by mixing the contents of partially damaged mitochondria as a form of complementation.
Mechanisms of Mitochondrial Fission and Fusion - PMC
Fission and fusion are important for growth, for mitochondrial redistribution, and for maintenance of a healthy mitochondrial network. In addition, mitochondrial fission and fusion play prominent roles in disease-related processes such as apoptosis and mitophagy.
Mitochondrial Fusion: The Machineries In and Out - PubMed
Here, we review recent advances in structural studies of the mitochondrial fusion machinery, discuss their implication for DLPs, and summarize the pathogenic mechanisms of disease-causing mutations in mitochondrial fusion DLPs.
Mitochondrial Fusion: The Machineries In and Out - Cell Press
2020年10月19日 · Here, we review recent advances in structural studies of the mitochondrial fusion machinery, discuss their implication for DLPs, and summarize the pathogenic mechanisms of disease-causing mutations in mitochondrial fusion DLPs.
Mitochondrial Fusion - an overview | ScienceDirect Topics
Mitochondrial fusion is a process by which two adjacent mitochondria are fused to form a more elongated mitochondria (or mitochondrial network). In mammals, this process is regulated by three large GTPases, mitofusin 1 (MFN1), mitofusin 2 (MFN2) and optic atrophy gene 1 (OPA1).
Mitochondrial fusion and fission in cell life and death
Mitochondria are dynamic organelles that constantly fuse and divide. These processes (collectively termed mitochondrial dynamics) are important for mitochondrial inheritance and for the maintenance of mitochondrial functions.