Sickle Cell Disease - Causes and Risk Factors | NHLBI, NIH
2024年8月20日 · Inheriting a faulty hemoglobin S gene from both parents causes sickle cell disease. Genetic counseling can help those at risk of having a child with sickle cell disease.
Sickle Cell Disease - What Is Sickle Cell Disease? - NHLBI, NIH
2024年9月30日 · The medicine was used to prevent sickling in red blood cells. Pfizer said the benefits of using voxelotor do not outweigh the risks in the approved sickle cell population. Sickle cell disease — also called sickle cell anemia — is a group of inherited disorders that affect hemoglobin , the major protein that carries oxygen in red blood cells.
Sickle Cell Disease - Treatment | NHLBI, NIH
2024年9月30日 · First line medicine to prevent sickling and reduce complications Hydroxyurea is an oral medicine that is frequently prescribed to help treat sickle cell disease. Hydroxyurea is an oral medicine that can reduce sickling of red blood cells and help prevent serious symptoms of sickle cell disease, including pain crises.
Sickle Cell Disease - Diagnosis | NHLBI, NIH
2024年9月9日 · Testing people with symptoms or newborns for blood and genetic abnormalities can find the presence of sickle cell disease.
How Sickle Cell Disease May Affect Your Health - NHLBI, NIH
2024年8月22日 · Joint problems: Sickling can occur in the hip bones and, less commonly, the shoulder joints, knees, and ankles. This can lower oxygen flow and result in a condition called avascular or aseptic necrosis, which seriously damages the joints.
Researchers study a new way to treat sickle cell disease
2022年6月16日 · Other anti-sickling therapies have targeted the problem in conventional ways by looking at how to increase the size of red blood cells, how to improve cell hydration, how to improve hemoglobin binding of oxygen, and how to increase fetal hemoglobin. The goal of these therapies has been to help cells deliver oxygen to tissues throughout the body.
Sickle Cell Disease - Symptoms | NHLBI, NIH
2024年8月20日 · Sickle cell disease is an inherited disease, which means you are born with it. However, most babies do not have problems from the disease before they are about 5 or 6 months old.
Sickle cell patient’s recovery after gene therapy ... - NHLBI, NIH
2019年3月12日 · The cells are then returned to the patients, leading to the production of anti-sickling hemoglobin (T87Q). Based on preliminary findings, which were presented at the latest meeting of the American Society of Hematology, researchers believe the new gene replacement therapy will enable the patients’ bone marrow to produce normal red blood cells ...
Researchers explore ways to help sickle cell disease patients …
2021年2月1日 · When the sudden onset of pain, the result of red blood cells sickling together, becomes unbearable, they can end up in the emergency room. A study in Scientific Reports, supported by NHLBI, assessed the role new approaches, like nutrition and friendship, may have in alleviating SCD-induced pain and in minimizing the use of opioids.
Sickle Cell Disease - Sickle Cell Trait - NHLBI, NIH
2024年8月22日 · People with sickle cell trait carry only one copy of the sickle hemoglobin gene and rarely have any symptoms of sickle cell disease.